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Name:Frog, edibleScientific Name:Rana esculentaOccurrence:Generally as cooked frogs legs.Allergy Information:There are few reports that allergy to frog, return at least three cases with serious symptoms have been reported. This allergy appears to happen after individuals build allergy come fish in most instances although two instances have been reported i beg your pardon seem come show direct sensitisation by frog. Other Information:This entry additionally contains info on various other edible frogs consisting of the bullfrog, Rana catesbeiana (NEWT 8400, ITIS 173441).Taxonomic Information:NEWT 8401 , ITIS 665307Last modified:18 October 2006

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You are watching: Can you be allergic to frogs

Clinical History

number of Studies:1-5Number of Patients:1-5

Skin Prick Test

variety of Studies:1-5

IgE assay (by RAST, lid etc)

variety of Studies:0

Immunoblotting

Oral provocation

variety of Studies:0Food used and also oral provocation vehicle:Blind:Number that Patients:Dose response:Symptoms:

IgE cross-reactivity and also Polysensitisation


Hamada et al. (2004) <1586> and also Hilger et al. (2004) <1365> present that frog parvalbumins cross-react through those from fin fish. The patient of Romano et al. (2000) <1716> was also fish allergic. However, the instances reported through Hilger et al. (2002) <1587> and Steurich (1996) <1715>show the frog allergy can additionally occur independently.


Occupational asthma and also allergy come frogs has been report (Charpin, 1953 <1720>; Nakazawa et al. 1983 <1721>; Armentia et al. 1988 <1722>; Holtz et al. 1993 <1723>). Outside of the small group the edible frogs, countless frogs contain toxin or venoms. Call with this frogs can produce symptoms request careful evaluation including the possibility of an allergy reaction (Forbes et al. 1995 <1718>).

Biochemical info for Alpha-parvalbumin

Allergen Name:Alpha-parvalbumin Alternatve Allergen Names:Ran e 1 Allergen Designation:None succession Known?:Yes 3D structure Accession No.:N/A calculated Masses:11929 Da speculative Masses:10-12 kDa Oligomeric Masses:Not well-known Allergen stability:Process, chemical, enzymatic:Most parvalbumins easily refold in the existence of calcium and thus allergenicity survives cooking. Allergen nature & organic function:Parvalbumins regulate the circulation of calcium indigenous troponin C earlier to membrane tied pumps after a muscle contraction. Each parvalbumin have the right to bind 2 calcium or (with lower affinity) magnesium ions.

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Biochemical info for Beta-parvalbumin

Allergen Name:Beta-parvalbumin Alternatve Allergen Names:Ran e 2 Allergen Designation:Major sequence Known?:Yes 3D framework Accession No.:N/A calculate Masses:11712 Da experimental Masses:10-12 kDa Oligomeric Masses:Not recognized Allergen stability:Process, chemical, enzymatic:Most parvalbumins easily refold in the existence of calcium and also thus allergenicity survives cooking. Allergen nature & organic function:Parvalbumins control the circulation of calcium indigenous troponin C ago to membrane bound pumps after ~ a muscle contraction. Each parvalbumin deserve to bind 2 calcium or (with lower affinity) magnesium ions.

References (4)